SubtiBank SubtiBank
yvqK [2017-8-11 16:0:3]
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yvqK [2017-8-11 16:0:3]

ATP:cob(I)alamin adenosyltransferase
locus
BSU33150
pI
5.21
mw
21.34 kDa
protein length
193 aa Sequence Blast
gene length
579 bp Sequence Blast
function
unknown
product
ATP:cob(I)alamin adenosyltransferase
essential
no
ec
2.5.1.17
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.13|Biosynthesis/ acquisition of cobalamine (B12))]
  • [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

    • Gene

    Coordinates
    3,400,537 → 3,401,118

    The protein

    Catalyzed reaction/ biological activity

  • ATP + cob(I)yrinic acid a,c-diamide = triphosphate + adenosylcob(III)yrinic acid a,c-diamide (according to Swiss-Prot)

    • Protein family

  • Cob(I)alamin adenosyltransferase family (according to Swiss-Prot)

    • Structure

  • [PDB|1RTY]

    • Expression and Regulation

    Operons

    genes
    [gene|C76265F521D9A153F28AC6BACD935CC20DEA5D9C|yvrC]-[gene|1DC4A3D7E93677B0EAD15F43C80E50FD98527EBC|yvrB]-[gene|128EBAE9C14C7BB75173DF912853A6FCE86ABCE4|yvrA]-[gene|468D9141EAC78556C9F6C564875F70EC43E60C1C|yvqK]

    regulatory mechanism

  • [regulon|B12 riboswitch|B12 riboswitch]: termination, upon binding of B12 [Pubmed|14704351], in [regulon|B12 riboswitch|B12 riboswitch]

    • regulation

  • expression is decreased in the presence of cobalamin (vitamin B12) ([SW|B12 riboswitch]) [Pubmed|14704351]
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    Biological materials

    Mutant

  • MGNA-B042 (yvqK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1041 NBRP B. subtilis, Japan]

    • References

  • 17588214,14704351